First of all, just in case you are asking What are nameservers? Now that is out of the way.
To make DNS changes at Enom.com, log in to your account and follow this guide.
1. Select the domain to change and click ‘Change’
2. Select the ‘User’ option to indicate you wish to specify your own name servers, then click ‘Save Changes’
3. Enter the new nameservers in the 1st and 2nd fields, then click ‘Save Changes’
Note: You need to enter a minimum of 2 nameservers.
Warning: Do not enter your IP address; this will cause problems.
Remember, it can take up to 72 hours for the changes to take effect.